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Mega-scale experimental analysis of protein folding stability in biology and design

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Method for measuring protein folding stability developed — Contributing to identification and drug discovery and creating a basis for AI development., News

Mega-scale experimental analysis of protein folding stability in biology and protein design

Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation

ROCKLIN LAB @ NORTHWESTERN CHICAGO - About

Protein design and variant prediction using autoregressive generative models

PDF) The new mega dataset combined with a deep neural network makes progress in predicting the impact of single mutations on protein stability

Mega-scale experimental analysis of protein folding stability in biology and protein design

Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation. - Abstract - Europe PMC

Protein folding stability measured at scale

Mega-scale experimental analysis of protein folding stability in biology and protein design

Exploiting enzyme evolution for computational protein design: Trends in Biochemical Sciences

Consequences of Genetic Recombination on Protein Folding Stability

Transfer learning to leverage larger datasets for improved prediction of protein stability changes